The Main Street Grille is located 15 minutes south, I-95 from Mystic, CT on the shoreline of the Niantic Bay and Long Island Sound, in Niantic CT.  Great food at reasonable prices open 7 days a week. Check out the view when the weather is nice on our outdoor patio or deck. Family casual, business meetings, special occasions, large or small. We cater to your details, with pride!